Endocrine Abstracts

Introduction: Transgender women and gender diverse individuals with functioning testicles who are eligible for estrogen-based hormone therapy need to use antiandrogens in addition to estrogen to achieve adequate desired physical changes and suppress testosterone to cisgender women levels. Sublingually administered estradiol can achieve higher serum estradiol levels than traditionally administered oral estradiol, but may require multidaily dosing (1). We present a case of trans...

Background: Sex based differences in the immune system are well-documented in the literature. The influence of sex on the immune system is primarily attributed via chromosomal and sex hormone mediation. Cis men generally exhibit a weaker immune response compared to cis women. This contrast extends to various immune-mediated diseases, where cis men show a higher incidence of cancer but fewer autoimmune diseases than cis women. Testosterone is part of gender affirming masculiniz...